Palmoplantar psoriasis: A phenotypical and clinical review with introduction of a new quality-of-life assessment tool - 08/08/11
Abstract |
Background |
Palmoplantar psoriasis is associated with significant quality-of-life issues. Its epidemiology and phenotypical expression remain ill defined.
Objective |
We reviewed the literature and our clinical experience and developed a new quality-of-life assessment tool.
Methods |
We conducted a retrospective review of 150 patients with palmoplantar psoriasis.
Results |
In all, 78 (52%) patients displayed predominantly hyperkeratotic palmoplantar lesions, 24 (16%) pustular, 18 (12%) combination, and 30 (20%) had an indeterminate phenotype. In 27 (18%) patients, lesions were confined to the palms and soles. A new quality-of-life index was constructed to characterize disease severity. In all, 27 (18%) had mild, 72 (48%) moderate, and 51 (34%) severe disease involvement. Palmoplantar disease severity appeared independent from the degree of body surface area involvement.
Limitations |
This was a retrospective review. The quality-of-life index remains to be statistically verified in prospective clinical studies.
Conclusion |
Defining morphologic subtypes together with the use of a specific quality-of-life assessment tool in patients with palmoplantar psoriasis will improve our understanding and treatment of this recalcitrant form of psoriasis.
Le texte complet de cet article est disponible en PDF.Key words : hand and foot questionnaire, new assessment tool, palmoplantar psoriasis, phenotype, quality-of-life assessment tool
Abbreviations used : BSA, IRB, PPP
Plan
Funding sources: None. |
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Conflicts of interest: None declared. |
Vol 60 - N° 6
P. 1024-1031 - juin 2009 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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