Incidence of nonmelanoma skin cancer in a cohort of patients with vitiligo - 08/08/11
Reprint requests: Henry W. Lim, MD, Department of Dermatology, Henry Ford Hospital, 3031 W Grand Blvd, Suite 800, Detroit, MI 48202.Abstract |
Background |
Nonmelanoma skin cancer (NMSC) incidence in patients with vitiligo has not been studied.
Objective |
We sought to quantify the incidence of NMSC in patients with vitiligo.
Methods |
A cohort of 477 patients with vitiligo and no history of NMSC seen in an outpatient academic center between January 2001 and December 2006 was established. All charts for patients with vitiligo were reviewed for incident NMSC, and histopathology verified. Age-adjusted (2000 US Standard Million) incidence rates were calculated and compared to US rates.
Results |
Six patients with NMSC were identified; all were Caucasian (>61 years). Age-adjusted incidence rates were: basal cell carcinoma, male 1382/100,000; basal cell carcinoma, female 0; squamous cell carcinoma, male 465/100,000; squamous cell carcinoma, female 156/100,000. Except for basal cell carcinoma in females, all rates were higher than US rates but not statistically significant.
Limitations |
Comparison incidence rates from the general patient population during the same time period were unavailable.
Conclusion |
Health care providers should be aware of the possible risk of NMSC in Caucasian patients with vitiligo.
Le texte complet de cet article est disponible en PDF.Abbreviations used : BCC, HFHS, KPNW, NH, NMSC, PUVA, SCC, UV
Plan
| Supported by the Departments of Dermatology and Biostatistics and Research Epidemiology, Henry Ford Hospital, and a Career Development Award from the Dermatology Foundation (Dr Eide). Department resources supported work on this project, including special histopathologic immunostaining. |
|
| Conflicts of interest: None declared. |
|
| Presented as podium presentations at the 68th Annual Meeting of the Society of Investigative Dermatology, Los Angeles, California, May 12, 2007, and at the 21st World Congress of Dermatology, Buenos Aires, Argentina, October 3, 2007. |
Vol 60 - N° 6
P. 929-933 - juin 2009 Retour au numéro
Article précédent
- American Board of Dermatology Examination Dates
- Randomized, double-blind, double-dummy, vehicle-controlled study of ingenol mebutate gel 0.025% and 0.05% for actinic keratosis
- Lawrence Anderson, George J. Schmieder, W. Philip Werschler, Eduardo H. Tschen, Mark R. Ling, Dow B. Stough, Janelle Katsamas
Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
Déjà abonné à cette revue ?