Evaluation of the treatment of port-wine stains with the 595-nm long pulsed dye laser: A large prospective study in adult Japanese patients - 09/08/11
Tokyo, Japan
Abstract |
Background |
Treatments of port-wine stains with conventional pulsed dye laser yield inconsistent results.
Objective |
We evaluated the efficacy and safety of the longer pulse duration 595-nm dye laser.
Methods |
Sixty-six adult Japanese patients were enrolled in this prospective study. The laser treatment with a cooling device was repeated 4 times at 8-week intervals with a consistent setting of 10-ms pulse duration and an energy fluence of 12 J/cm2, using 7-mm spot size.
Results |
Improvement of port-wine stains was observed after multiple treatments, and 67% of the patients achieved either good or excellent response after the fourth treatment. Transient purpura, edema, or both were noted immediately after each treatment (76%-79% and 58%-67%, respectively). Hyperpigmentation (8%-17%) and hypopigmentation (6%-14%) were also mild and their occurrence did not increase by repeating treatments.
Limitations |
Eighty five percent of the patients were classified as having Fitzpatrick skin type IV.
Conclusion |
Our study indicated that the 595-nm dye laser with 10-ms pulse duration may be effective and well tolerated in the treatment of port-wine stains in adult Asians.
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Funding sources: Candela Corporation provided financial support for the institutional, IRB-approved study. Conflict of interest: Equipment provided by Candela Corporation. |
Vol 54 - N° 3
P. 487-493 - mars 2006 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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