Fibrous hamartoma of infancy: An Italian multi-institutional experience - 09/08/11
, Rita Alaggio, MD b, Fortunato Siracusa, MD c, Claudio Granata, MD d, Andrea Ferrari, MD e, Giovanni Cecchetto, MD a
Reprint requests: Patrizia Dall’Igna, MD, Paediatric Surgery Department, University of Padua, Via Giustiniani 3, 35128 Padua, Italy.Padua, Palermo, Genoa, and Milan, Italy
Abstract |
Background |
Fibrous hamartoma (FH) of infancy is a benign mesenchymal tumor, occurring as a superficial mass. Complete excision is curative.
Objective and Methods |
The clinical features and treatment results of 18 children with FH are described.
Results |
Local excision was the most common procedure. Surgery was radical in 10 patients, with microscopic residual disease in 6; all of them are alive with no evidence of disease 2 to 49 months after diagnosis. One patient, treated with a local reexcision for macroscopic residual disease (and chemotherapy for a synchronous desmoid fibromatosis) is well 83 months after diagnosis; the last patient, with a lesion of the labia majora, only underwent biopsy and is doing well, awaiting plastic surgery.
Limitations |
The results did not reach statistical significance due to difficulties in collecting cases.
Conclusions |
FH should be treated by complete excision; in our experience a nonradical excision was also able to achieve the cure. An aggressive approach should be avoided, as the overall prognosis is excellent.
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| Funding sources: None. Conflicts of interest: None identified. |
Vol 54 - N° 5
P. 800-803 - mai 2006 Retour au numéro
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