Treatment of refractory subacute cutaneous lupus erythematosus with efalizumab - 09/08/11
, Stephanie Ogden, MB CHB, MRCP, Mark D.J. Goodfield, MB CHB, MD, FRCP
Reprint requests: Dr Timothy Howel Clayton, MB CHB, MRCPCH(UK), Department of Dermatology, Leeds General Infirmary, Great George St, Leeds LS1 3EX, United KingdomLeeds, United Kingdom
Abstract |
We report the case of a 47-year-old woman who first presented with erythematous plaques on the upper portion of her right arm, which developed into an annular eruption involving the face, upper portion of the trunk, and limbs in a predominantly photosensitive distribution. Findings from histopathologic evaluation of a lesion from her arm were consistent with the clinical diagnosis of SCLE. After years of unsuccessful treatment with conventional medications for SCLE, she began therapy with efalizumab and experienced dramatic improvement in her cutaneous lesions after 6 weeks.
Le texte complet de cet article est disponible en PDF.Abbreviations used : LFA-1, ICAM-1, SLCE, TNF
Plan
| Funding sources: None. Conflicts of interest: None identified. |
Vol 54 - N° 5
P. 892-895 - mai 2006 Retour au numéro
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