Smith-Magenis syndrome: A case report of improved sleep after treatment with β1-adrenergic antagonists and melatonin - 09/08/11
Doi : 10.1016/j.jpeds.2006.04.055
Rosario Carpizo, MD, PhD, Ángeles Martínez, MD, Dolores Mediavilla, MD, PhD, Mónica González, MD, Araceli Abad, MD, Emilio J. Sánchez-Barceló, MD, PhD ⁎ 
Unit of Sleep Disorders, University Hospital “Marqués de Valdecilla” (HUMV), and the Department of Physiology and Pharmacology, School of Medicine, University of Cantabria, Santander, Spain.
Reprint requests: Dr Emilio J. Sánchez-Barceló, Department of Physiology and Pharmacology, University of Cantabria, Herrera Oria s/n, 39011 Santander, Spain.Résumé |
This report describes the case of a 4-year-old boy diagnosed with Smith-Magenis syndrome in whom treatment with a β1-adrenergic antagonist in the morning (to suppress the diurnal melatonin secretion) and melatonin in the evening (to generate a nocturnal peak of melatonin) improved his sleep quality, evaluated by polysomnographic studies.
Le texte complet de cet article est disponible en PDF.Abbreviations : REM, SMS, TST
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Vol 149 - N° 3
P. 409-411 - septembre 2006 Retour au numéro
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