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Joint Bone Spine
Volume 72, n° 4
pages 326-329 (juillet 2005)
Doi : 10.1016/j.jbspin.2004.06.004
Received : 23 December 2003 ;  accepted : 30 June 2004
Acitretin-induced enthesitis in a patient with psoriatic arthritis
 

Véronique Vincent a, , Laurent Zabraniecki a, Olivier Loustau b, Bertrand Godfrin a, Frédérique Bertrand Latour a, Jean-Jacques Railhac b, Bernard Fournié a
a Rheumatology Department, CHU Purpan Teaching Hospital, place du Docteur Baylac, 31059 Toulouse, France 
b Central Medical Imaging Department, Purpan Teaching Hospital, place du Docteur Baylac, 31059 Toulouse, France 

*Corresponding author. Tel.: +33-5-61-77-25-62; fax: +33-5-61-77-22-08.
Abstract

A patient with psoriatic arthritis and cutaneous psoriasis took acitretin for 10 years to treat his skin lesions. Radiographs disclosed exuberant ossifications in several entheses. Their features were not typical for psoriatic arthritis but were consistent with acitretin-induced hyperostosis. Retinoids are known to induce hyperostosis, most notably when they are used in high dosages and over long periods. The concomitant presence of two conditions affecting the entheses may explain the exuberant nature of the ossifications in our patient.

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Keywords : Retinoids, Entheses, Psoriatic arthritis




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