Quality of life in cutaneous lupus erythematosus - 10/08/11
Reprint requests: Victoria P. Werth, MD, Department of Dermatology, Perelman Center for Advanced Medicine, Suite 1-330A, 3400 Civic Center Blvd, Philadelphia, PA 19104.Abstract |
Background |
Little is known about quality of life in patients with cutaneous lupus erythematosus.
Objective |
We sought to determine how cutaneous lupus affects quality of life and which independent variables are associated with poor quality of life.
Methods |
A total of 157 patients with cutaneous lupus completed surveys related to quality of life, including the Skindex-29 and the Short Form-36.
Results |
Quality of life in cutaneous lupus is severely impaired, particularly with respect to emotional well-being. Patients with cutaneous lupus have worse quality of life than those with other common dermatologic conditions, such as acne, nonmelanoma skin cancer, and alopecia. With respect to mental health status, patients with cutaneous lupus have similar or worse scores than patients with hypertension, type 2 diabetes mellitus, recent myocardial infarction, and congestive heart failure. Factors related to poor quality of life include female gender, generalized disease, severe disease, distribution of lesions, and younger age.
Limitations |
The study was done at a single referral-only center.
Conclusion |
Patients with cutaneous lupus have very impaired quality of life, particularly from an emotional perspective.
Le texte complet de cet article est disponible en PDF.Key words : cutaneous lupus erythematosus, Cutaneous Lupus Erythematosus Disease Area and Severity Index, psychiatric comorbidity, quality of life, Short Form-36 (SF-36), Skindex-29
Abbreviations used : ACLE, BP, CLASI, DLE, GH, MH, PF, RE, SCLE, SF-36, SLE
Plan
| This material is based on work supported by the National Institutes of Health, including NIH K24-AR 02207 (Dr Werth), NIH K24 AR052667 (Dr Chren), and training grant NIH T32-AR007465-25 (Ms Klein). This work was also partially supported by a Merit Review Grant from the Department of Veterans Affairs Veterans Health Administration, Office of Research and Development, Biomedical Laboratory Research and Development. |
|
| Conflicts of interest: None declared. |
Vol 64 - N° 5
P. 849-858 - mai 2011 Retour au numéro
Article précédent
- Delayed treatment and continued growth of nonmelanoma skin cancer
- Murad Alam, Leonard H. Goldberg, Sirunya Silapunt, Erin S. Gardner, Sara S. Strom, Alfred W. Rademaker, David J. Margolis
- Dermatoscopy of genital warts
- Huiting Dong, Dan Shu, Terri M. Campbell, Julia Frühauf, Peter Soyer, Rainer Hofmann-Wellenhof
Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
Déjà abonné à cette revue ?