Adverse reactions to injectable soft tissue fillers - 10/08/11
Abstract |
In recent years, injections with filler agents are often used for wrinkle-treatment and soft tissue augmentation by dermatologists and plastic surgeons. Unfortunately, the ideal filler has not yet been discovered and all of them may induce adverse reactions. Quickly biodegradable or resorbable agents may induce severe complications, but they will normally disappear spontaneously in a few months. Slowly biodegradable or nonresorbable fillers may give rise to severe reactions that show little or no tendency to spontaneous improvement. They may appear several years after the injection, when the patient does not remember which product was injected, and treatment is often insufficient. In this review, we discuss the most commonly used fillers, their most frequent adverse reactions as well as the characteristic histopathologic findings that allow the identification of the injected filler agent. In conclusion, histopathologic study remains as the gold standard technique to identify the responsible filler.
Learning objectives |
After completing this learning activity, participants should be able to recognize the most frequent adverse reactions induced by cosmetic fillers, identify their histopathologic characteristics so that they can be distinguished from each other, and advise their patients with adverse reactions about the different nature of these according to the filler for subsequent successful treatment.
Le texte complet de cet article est disponible en PDF.Key words : adverse reactions, bovine collagen, calcium hydroxylapatite, dextranomers, fillers, histopathology, hyaluronic acid, paraffin, polyacrylamide, polyalkylimide, poly-L-lactic acid, polymethylmethacrylate, polyvinylhydroxide, polyvinylpyrrolidone, silicone
Plan
Robert T. Brodell, MD, JAAD CME Planner, has disclosed the following financial relationship: Medicis - Advisory Board/Honoraria. All other authors, editors, planners, editorial and education staff involved with this CME activity and all content validation/peer reviewers of this journal-based CME activity have reported no relevant financial relationships with commercial interest(s). |
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Reprints not available from the authors. |
Vol 64 - N° 1
P. 1-34 - janvier 2011 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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