Acrodermatitis enteropathica and an overview of zinc metabolism - 12/08/11
Doi : 10.1016/j.jaad.2006.08.015
Emanual Maverakis, MD a, Maxwell A. Fung, MD a, b, Peter J. Lynch, MD a, Michelle Draznin, MD a, Daniel J. Michael, MD, PhD a, Beth Ruben, MD c, Nasim Fazel, MD, DDS a, ⁎ 
a From the Departments of Dermatology
b Pathology, University of California–Davis, Sacramento
c Department of Dermatology, University of California–San Francisco
Reprint requests: Nasim Fazel, MD, DDS, Department of Dermatology, University of California–Davis, 3301 C St, Suite 1412, Sacramento, CA 95816.Sacramento and San Francisco, California
Abstract |
Acrodermatitis enteropathica is a rare autosomal recessive disorder of zinc deficiency. The genetic defect has been mapped to 8q24 and the defective gene identified as SLC39A4, which encodes the zinc transporter Zip4. The diagnosis is made by way of clinical presentation together with histopathology and laboratory tests. Here we provide an overview of zinc metabolism and a description of inherited and acquired zinc deficiency.
Le texte complet de cet article est disponible en PDF.Abbreviations used : AE, lm, SLC
Plan
| Funding sources: None. Conflicts of interest: None identified. |
© 2007
American Academy of Dermatology, Inc.. Publié par Elsevier Masson SAS. Tous droits réservés.
Vol 56 - N° 1
P. 116-124 - janvier 2007 Retour au numéro
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