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Archives de pédiatrie
Volume 18, n° 9
pages 966-969 (septembre 2011)
Doi : 10.1016/j.arcped.2011.06.003
Received : 13 February 2010 ;  accepted : 10 June 2011
Syndrome de Sweet révélateur d’une leucémie
Sweet syndrome revealing leukemia
 

E. Elleuch a, , B. Hammami a, F. Smaoui b, I. Maaloul a, H. Turki b, M. Elloumi c, M. Ben Jemaa a
a Service des maladies infectieuses, CHU Hedi-Chaker, Sfax, Tunisie 
b Service de dermatologie, CHU Hedi-Chaker, Sfax, Tunisie 
c Service d’hématologie, CHU Hedi-Chaker, Sfax, Tunisie 

Auteur correspondant.
Résumé

Le syndrome de Sweet fait partie des dermatoses neutrophiliques et peut orienter vers des pathologies diverses, notamment inflammatoires et néoplasiques. Nous rapportons un cas de syndrome de Sweet révélateur d’une leucémie aiguë chez une enfant de 13ans, qui n’avait aucun antécédent pathologique. Le diagnostic était évoqué malgré des lésions cutanées atypiques et confirmé par la biopsie cutanée et l’étude du myélogramme. Malgré une chimiothérapie avec corticothérapie, l’enfant décédait rapidement. Le diagnostic de syndrome de Sweet impose une enquête étiologique exhaustive. En l’absence de cause évidente, une surveillance régulière est indiquée afin de ne pas méconnaître une pathologie sous-jacente.

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Summary

Sweet syndrome is a neutrophilic dermatosis that can lead to various inflammatory and neoplastic pathologies. We report a case of Sweet syndrome revealing acute leukemia at a 13-year-old girl, who had no history of illness. The diagnosis was made in spite of atypical skin lesions and was confirmed by the skin biopsy and the bone marrow examination. In spite of corticosteroid therapy and chemotherapy, the patient died. Sweet syndrome’s diagnosis requires an exhaustive etiologic survey. If there is no evidence of underlying disease, patients must be regularly monitored.

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