In vivo reflectance confocal microscopy imaging of melanocytic skin lesions: Consensus terminology glossary and illustrative images - 19/08/11
Reprint requests: Salvador Gonzalez, MD, PhD, Dermatology Service, Memorial Sloan-Kettering Cancer Center, 160 E 53rd St, 2nd Floor, New York, NY 10022.Abstract |
Background |
Reflectance confocal microscopy (RCM) has been used for over 10 years for in vivo skin imaging. However, to date no standard RCM terminology has been published.
Objective |
To establish a glossary of terms for RCM evaluation of melanocytic lesions.
Methods |
Prominent RCM researchers were presented with RCM images of melanocytic lesions. Reviewers evaluated RCM images for image quality, lesion architecture, and cellular details. Reviewers could utilize published descriptors or contribute unpublished terminology to describe lesion attributes. An online meeting was conducted to reach consensus that integrates and defines existing and new RCM descriptive terms.
Results |
We present a glossary with descriptors of image quality, normal skin morphology, lesion architecture, and cellular details for RCM evaluation of melanocytic lesions.
Limitations |
Usefulness of the glossary in RCM diagnosis of melanocytic lesions needs to be assessed.
Conclusion |
Standardization of terminology is important toward implementation of RCM in the clinical setting.
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| Drs Scope and Benvenuto-Andrade contributed equally to this report. |
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| Funding sources: None. |
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| Disclosure: Dr Rajadhyaksha is a former employee of Lucid Inc., the company that makes and sells the VivaScope confocal microscope. He owns stock options in Lucid. The VivaScope is the commercial version of an original laboratory prototype of a confocal scanning laser microscope that was developed by Rajadhyaksha when he was in the Department of Dermatology at Massachusetts General Hospital, Harvard Medical School. Drs Scope, Benvenuto-Andrade, Agero, Malvehy, Puig, Busam, Marra, Torres, Propperova, Langley, Marghoob, Pellacani, Seidenari, Halpern, and Gonzalez have no conflicts of interest to declare. |
Vol 57 - N° 4
P. 644-658 - octobre 2007 Retour au numéro
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