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Journal of the American Academy of Dermatology
Volume 57, n° 4
pages 665-668 (octobre 2007)
Doi : 10.1016/j.jaad.2007.03.020
Dermatopathology

Giant verrucous porokeratosis of Mibelli mimicking psoriasis in a patient with psoriasis
 

Clara De Simone, MD a, Andrea Paradisi, MD a, , Guido Massi, MD b, Ilaria Proietti, MD a, Angela Capponi, MD a, Pier Luigi Amerio, MD a, Rodolfo Capizzi, MD a
a Departments of Dermatology and Venereology, Università Cattolica del Sacro Cuore, Rome, Italy 
b Department of Anatomic Pathology, Università Cattolica del Sacro Cuore, Rome, Italy 

Correspondence to: Andrea Paradisi, MD, Department of Dermatology, Policlinico A. Gemelli, Università Cattolica del Sacro Cuore, Largo Gemelli 8 - 00168 Rome, Italy.
Abstract

Porokeratosis of Mibelli is a disorder of epidermal keratinization characterized by annular plaques with an atrophic center surrounded by a keratotic wall. We report a case of a giant verrucous porokeratosis of Mibelli mimicking psoriasis that developed in a patient with psoriasis and therefore went unrecognized for a long time. Histologically the lesion combined features of porokeratosis at the periphery and of psoriasis at its center, a picture recently described as “psoriasis encircled by porokeratosis.” The possible pathogenetic relationship between psoriasis and the development of porokeratosis is also discussed.

The full text of this article is available in PDF format.

 Funding sources: None.
 Conflicts of interest: None declared.
 Reprints not available from the authors.



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