Contact dermatitis of the hands: Cross-sectional analyses of North American Contact Dermatitis Group Data, 1994-2004 - 19/08/11
, Rehana L. Ahmed, MD, PhD b, Donald V. Belsito, MD c, Vincent A. DeLeo, MD d, Joseph F. Fowler, MD e, Howard I. Maibach, MD f, James G. Marks, MD g, C.G. Toby Mathias, MD h, Melanie D. Pratt, MD i, Robert L. Rietschel, MD j, Denis Sasseville, MD k, Frances J. Storrs, MD l, James S. Taylor, MD m, Kathryn A. Zug, MD n
Correspondence to: Erin M. Warshaw, MD, MS, Dermatology Department 111K, Veterans Affairs Medical Center, One Veterans Drive, Minneapolis, MN 55417.Minneapolis, Minnesota; Shawnee, Kansas; New York, New York; Louisville, Kentucky; San Francisco, California; Hershey, Pennsylvania; Cincinnati and Cleveland, Ohio; Ottawa, Ontario and Montreal, Quebec, Canada; Tucson, Arizona; Portland, Oregon; and Lebanon, New Hampshire
Abstract |
Background |
Hand dermatitis, including irritant and allergic contact dermatitis (ACD), is common.
Objective |
To evaluate allergens, relevant irritants, sources and occupations associated with hand contact dermatitis using North American Contact Dermatitis Group (NACDG) data.
Methods |
A cross-sectional analysis of 22,025 patients patch tested between 1994 and 2004.
Results |
Hand involvement was found in 6953 patients; 959 had ACD as the only diagnosis. In these 959 patients, the 12 most frequent relevant allergens were quaternium-15 (16.5%), formaldehyde (13.0%), nickel sulfate (12.2%), fragrance mix (11.3%), thiuram mix (10.2%), balsam of Peru (9.6%), carba mix (7.8%), neomycin sulfate (7.7%), bacitracin (7.4%), methyldibromoglutaronitrile/phenoxyethanol 2.0% (7.4%), cobalt chloride (6.5%), and methyldibromoglutaronitrile/phenoxyethanol 2.5% (6.3%). Rubber allergens were most commonly associated with occupation. One third of patients with hand ACD had identifiable relevant irritants.
Limitations |
Cross-sectional analyses prevent evaluation of causal associations.
Conclusion |
In NACDG patients with hand ACD, the most common allergens included preservatives, metals, fragrances, topical antibiotics, and rubber additives.
Le texte complet de cet article est disponible en PDF.Abbreviations used : ACD, ICD, MCCDG, NACDG
Plan
| Study funding sources: None. Grant support: National Institutes of Health T32 GM08244-15 (to R. L. A.). Conflicts of interest: None declared. Disclaimer: The views expressed in this article are those of the authors and do not necessarily reflect the position or policy of the Department of Veterans Affairs. Reprints not available from the authors. |
Vol 57 - N° 2
P. 301-314 - août 2007 Retour au numéro
Article précédent
- An outbreak of Paederus dermatitis in a suburban hospital in South India: A report of 123 cases and review of literature
- Pushpa Gnanaraj, V. Venugopal, M. Kuzhal Mozhi, C.N. Pandurangan
- Contact allergy in oral disease
- Rochelle R. Torgerson, Mark D.P. Davis, Alison J. Bruce, Sara A. Farmer, Roy S. Rogers
Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
Déjà abonné à cette revue ?