An in vitro study comparing temperatures of over-the-counter wart preparations with liquid nitrogen - 19/08/11
, Irene Pchalek, BIS b, Melissa Adler b, Craig N. Burkhart, MD, MSBS c
Reprint requests: Craig G. Burkhart, MD, MPH, University of Toledo College of Medicine, 5600 Monroe St, Suite 106B, Sylvania, OH 43560.Abstract |
Background |
Over-the-counter (OTC) wart-freezing therapies have appeared on the market claiming that they reproduce in-office cryotherapy.
Objective |
We sought to determine whether these OTC home wart removal products are as cold as liquid nitrogen.
Methods |
The coldness obtained by 3 representative commercial wart products, and liquid nitrogen, was assessed using a thermometer calibrated from –100°C to 50°C. Temperatures of the commercial wart products used were measured and compared with those obtained with liquid nitrogen.
Results |
None of the OTC coolants were as cold as liquid nitrogen, and they did not lower temperature as quickly as liquid nitrogen.
Limitations |
This study did not evaluate the clinical efficacy of any of the agents studied.
Conclusions |
Despite advertising messages, OTC refrigerants do not achieve freezing equivalent to liquid nitrogen.
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| Funding sources: None. |
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| Conflicts of interest: None declared. |
Vol 57 - N° 6
P. 1019-1020 - décembre 2007 Retour au numéro
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