Cutaneous responses to vaccinia in individuals with previous smallpox vaccination - 19/08/11
Portland, Oregon
Abstract |
The durability of immune responses to smallpox vaccine is a subject of considerable debate. We compared cutaneous vaccinia responses in patients vaccinated in the distant past with vaccine-naïve individuals using serial close-up photographs. The previously vaccinated group had a significantly reduced time course and milder cutaneous reactions. Vaccinated individuals appear to maintain clinically detectable immunity against vaccinia for at least 20 years after smallpox vaccination.
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Supported by National Institutes of Health grant AI063675 (Dr Slifka), Oregon National Primate Research Center grant RR00163 (Dr Slifka), and a Career Development Award from the Dermatology Foundation (Dr Simpson). Conflicts of interest: None declared. |
Vol 57 - N° 3
P. 442-444 - septembre 2007 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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