Life-threatening blood loss from scratching provoked by pruritus in the bulky perineal nevocytoma variant of giant congenital melanocytic nevus in a child - 21/08/11
Doi : 10.1016/j.jaad.2004.12.040
Jing Feng, BS a, Aisha Sethi, MD a, Miguel Reyes-Múgica, MD b, Richard Antaya, MD a, c, ⁎ 
a From the Departments of Dermatology
b Pathology
c Pediatrics, Yale University School of Medicine
Correspondence to: Richard Antaya, MD, Department of Dermatology, Yale University School of Medicine, PO Box 208059, New Haven, CT 06520-8059.New Haven, Connecticut
Abstract |
We describe a 3-year-old girl with intractable, debilitating pruritus associated with a giant congenital melanocytic nevus, resulting in life-threatening anemia from extensive bleeding skin excoriations. Multiple conventional oral and topical antipruritic medications failed to provide relief, but the patient was successfully treated with the selective serotonin 5-hydroxytryptamine type 3 inhibitor ondansetron, suggesting a serotonin-related mechanism to her pruritus.
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| Supported by Stiefel Laboratories. Funding sources: None. Conflicts of interest: None identified. Reprints not available from the authors. |
© 2005
American Academy of Dermatology, Inc.. Publié par Elsevier Masson SAS. Tous droits réservés.
Vol 53 - N° 2S
P. S139-S142 - août 2005 Retour au numéro
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