Primary cutaneous B-cell lymphoma - 21/08/11
Houston, Texas
Abstract |
Primary cutaneous B-cell lymphomas include extranodal marginal zone B-cell lymphoma, follicular lymphoma, large B-cell lymphoma, and, rarely, mantle cell lymphoma. Our purpose in conducting this review was to determine the clinical and behavioral characteristics of primary cutaneous B-cell lymphomas, their relationship to infectious triggers, and therapeutic response. We conducted a retrospective chart review of 23 adult patients presenting to the dermatology clinic at M. D. Anderson Cancer Center with primary cutaneous B-cell lymphoma between January 1999 and May 2003. Primary cutaneous B-cell lymphomas generally present on the head and neck, with the trunk and extremities afflicted to a lesser extent. Patients were found to have serologic evidence of prior infection with Borrelia burgdorferi (n=10), Helicobacter pylori (n=5), and Epstein-Barr virus (n=6). Overall, treatment of primary cutaneous B-cell lymphoma should involve multiple modalities; however, specific treatment aimed at concurrent or suspected infection, particularly B burgdorferi, is a helpful adjunct and may achieve complete remission in a small subset of patients.
Le texte complet de cet article est disponible en PDF.Abbreviations used : CHOP, CR, EORTC, LTFU, MALT, PCR, PR, WHO
Plan
Funding sources: None. Conflicts of interest: None identified. |
Vol 53 - N° 3
P. 478-483 - septembre 2005 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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