A bullous neutrophilic dermatosis in a patient with severe rheumatoid arthritis and monoclonal IgA gammopathy - 24/08/11
, Hong-Shang Hong, MD, PhD
Reprint requests: Chih-Hsun Yang, MD, Department of Dermatology, Chang Gung Memorial Hospital, 199, Tung Hwa N Rd, Taipei 105, Taiwan, Republic of China.Taipei, Taiwan
Abstract |
A 35-year-old man presented with a 2-month history of itchy grouped vesiculobullae with crusted papules and confluent plaques, distributed symmetrically on the thighs, knees, and elbows. The man had experienced severe disabling seropositive rheumatoid arthritis for 18 years previously. Histologically, subepidermal vesicles were noted, and a dense, diffuse neutrophilic infiltration of the dermis. Direct immunofluorescence studies did not detect IgA deposits. The patient responded well to dapsone (100 mg/d) but not to systemic steroids. This patient's eruption might have been an unusual manifestation of rheumatoid neutrophilic dermatitis.
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 | This supplement is made possible through the generous support of Stiefel Laboratories for the American Academy of Dermatology. Funding sources: None. Conflicts of interest: None identified. |
Vol 51 - N° 2S
P. 94-96 - août 2004 Retour au numéro
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