Progressive epidermotropic CD8+/CD4− primary cutaneous CD30+ lymphoproliferative disorder in a patient with sarcoidosis - 24/08/11
Philadelphia, Pennsylvania
Abstract |
We describe a patient with a CD8+/CD4− primary cutaneous CD30+ lymphoproliferative disorder with striking epidermotropic histology and coincident cutaneous and systemic sarcoidosis. This patient illustrates the spectrum of clinical and histologic features of CD30+ lymphoproliferative disorders and the need for adequate staging in such cases. This patient's CD30/CD8 coexpression is rare and has clinical and prognostic implications, including mucosally and acrally accentuated lesions and a potentially more aggressive course. Primary cutaneous CD30+ lymphoproliferative disorders have an excellent prognosis; therefore multiagent chemotherapy modalities are generally not indicated. The combination of T-cell lymphoma and sarcoidosis is also rare and may limit treatment options.
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Funding sources: None. Conflict of interest: None identified. Presented at the annual meeting of the Medical Dermatology Society, Washington, DC, March 2, 2001. |
Vol 51 - N° 2
P. 304-308 - août 2004 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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