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Gynécologie Obstétrique & Fertilité
Volume 34, n° 9
pages 716-719 (septembre 2006)
Doi : 10.1016/j.gyobfe.2006.05.005
Received : 23 Mars 2006 ;  accepted : 2 May 2006
Présentation inhabituelle d'un choriocarcinome gestationnel
Uncommon clinical presentation of a gestational choriocarcinoma
 

C. Regis a, S. Taieb b, A. Lesoin a, M.-C. Baranzelli c, T. Blehaut d, E. Leblanc a,
a Service de cancérologie gynécologique, centre de lutte contre le cancer (CLCC) Oscar-Lambret, BP 307, 3, rue Frédéric-Combemale, 59020 Lille cedex, France 
b Service de radiologie, centre de lutte contre le cancer (CLCC) Oscar-Lambret, BP 307, 3, rue Frédéric-Combemale, 59020 Lille cedex, France 
c Service d'anatomopathologie, centre de lutte contre le cancer (CLCC) Oscar-Lambret, BP 307, 3, rue Frédéric-Combemale, 59020 Lille cedex, France 
d Laboratoire d'anatomopatologie, 153, quai d'Alsace, 59509 Douai, France 

Auteur correspondant.
Résumé

Le choriocarcinome gestationnel est une tumeur maligne rare à fort potentiel métastatique. Nous rapportons le cas d'une patiente de 31 ans présentant un choriocarcinome gestationnel révélé par des métastases rénales et pulmonaires, un an après une grossesse normale. Le diagnostic fortuit a été fait par l'analyse anatomopathologique de la pièce de néphrectomie. L'évolution a été favorable après traitement adéquat par polychimiothérapie. Ce cas clinique souligne la symptomatologie polymorphe du choriocarcinome et permet d'insister sur l'importance du dosage de la βHCG pour le diagnostic.

The full text of this article is available in PDF format.
Abstract

Gestational choriocarcinoma is a rare malignant tumour with a strong metastatic potential. We report a case of a 31-year-old patient with a gestational trophoblastic tumor revealed by renal and pulmonary metastases, one year after a normal pregnancy. The diagnosis was established by the pathologist on the radical nephrectomy specimen. The evolution was quickly favorable after adequate treatment using multiagent chemotherapy. This case highlights the polymorphic aspects of the gestational choriocarcinoma and stresses the importance of a βHCG assessement anytime abnormal symptoms occur in the outcome of a pregnancy.

The full text of this article is available in PDF format.

Mots clés : Choriocarcinome gestationnel, Maladies trophoblastiques gestationnelles, Chimiothérapie

Keywords : Gestational choriocarcinoma, Gestational trophoblastic neoplasia, Chemotherapy




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