Article

Access to the text (HTML) Access to the text (HTML)
PDF Access to the PDF text
Advertising


Access to the full text of this article requires a subscription.
  • If you are a subscriber, please sign in 'My Account' at the top right of the screen.

  • If you want to subscribe to this journal, see our rates



Journal of the American Academy of Dermatology
Volume 48, n° 4
pages 477-496 (avril 2003)
Doi : 10.1067/mjd.2003.200
Hemangiomas of infancy
 

Anna L. Bruckner, MDa, Ilona J. Frieden, MDb
Aurora, Colorado, and San Francisco, California 
From the Department of Dermatology, University of Colorado,a and the Department of Dermatology and Pediatrics, University of California, San Francisco.b 

Abstract

Hemangiomas of infancy are unique, benign, pediatric tumors of endothelial cells characterized by an initial phase of rapid proliferation, followed by slow involution, often leading to complete regression. Although most of these tumors are small and innocuous, some may be may be life- or function-threatening, or have associated structural congenital anomalies. Uncertainties regarding their diagnosis or management often prompt referral to a dermatologist. The pathogenesis of hemangiomas of infancy is not well understood, but recent findings suggest a unique vascular phenotype with dysregulated vascular homeostasis. This article reviews new information regarding the pathogenesis of these tumors and highlights the more worrisome presentations, including syndromic hemangiomas, that are likely to be problematic. In addition, management strategies and treatment options are discussed. (J Am Acad Dermatol 2003;48:477-93.) Learning objective: At the completion of this learning activity, participants should be able to describe the clinical features of hemangiomas of infancy and potential complications as well as to understand the strengths and limitations of various treatment options.

The full text of this article is available in PDF format.

Abbreviations : CNS, CVS, HOI, NICH, PDL, RICH, VEGF



 Funding sources: None.
 Conflict of interest: None identified.
 Reprints not available from authors.
 Correspondence: Ilona J. Frieden, MD, Department of Dermatology, University of California, San Francisco, 1701 Divisadero St, 3rd Floor, San Francisco, CA 94143-0316. E-mail: ijfrieden@orca.ucsf.edu.
 0190-9622/2003/$30.00 + 0



© 2003  American Academy of Dermatology, Inc. Published by Elsevier Masson SAS@@#104157@@
EM-CONSULTE.COM is registrered at the CNIL, déclaration n° 1286925.
As per the Law relating to information storage and personal integrity, you have the right to oppose (art 26 of that law), access (art 34 of that law) and rectify (art 36 of that law) your personal data. You may thus request that your data, should it be inaccurate, incomplete, unclear, outdated, not be used or stored, be corrected, clarified, updated or deleted.
Personal information regarding our website's visitors, including their identity, is confidential.
The owners of this website hereby guarantee to respect the legal confidentiality conditions, applicable in France, and not to disclose this data to third parties.
Close
Article Outline