Article

Access to the text (HTML) Access to the text (HTML)
PDF Access to the PDF text
Advertising


Access to the full text of this article requires a subscription.
  • If you are a subscriber, please sign in 'My Account' at the top right of the screen.

  • If you want to subscribe to this journal, see our rates



Journal of the American Academy of Dermatology
Volume 48, n° 4
pages 525-529 (avril 2003)
Doi : 10.1067/mjd.2003.107
accepted : 5 April 2002
Lupus-associated toxic epidermal necrolysis: A novel manifestation of lupus?
 

Rochelle Mandelcorn, MD, FRCPC, Neil H. Shear, MD, FRCPC
Toronto, Ontario, Canada 
From the Division of Dermatology, Department of Medicine, University of Toronto 

Abstract

Background: Toxic epidermal necrolysis is an acute mucocutaneous reaction characterized by extensive cutaneous and mucosal sloughing and systemic involvement. It is generally associated with drug ingestion. Objective and Methods: We describe 2 patients who developed typical clinical and histopathologic features of toxic epidermal necrolysis with unusual subacute progression, absence of systemic involvement or high-risk drug ingestion, and features of lupus erythematosus. Conclusion: We propose that this constellation of features represents a new entity not previously described. This entity may represent a more severe variant of Rowell's syndrome or, alternatively, a novel manifestation of lupus erythematosus (J Am Acad Dermatol 2003;48:525-9.)

The full text of this article is available in PDF format.

 Funding sources: None.
 Conflict of interest: None identified.
 Reprint requests: Neil H. Shear, Division of Dermatology, Sunnybrook & Women's College Health Sciences Centre, 2075 Bayview Avenue, Toronto, Ontario, Canada, M4N 3M5. E-mail: neil.shear@swchsc.on.ca.
 0190-9622/2003/$30.00 + 0



© 2003  American Academy of Dermatology, Inc. Published by Elsevier Masson SAS@@#104157@@
EM-CONSULTE.COM is registrered at the CNIL, déclaration n° 1286925.
As per the Law relating to information storage and personal integrity, you have the right to oppose (art 26 of that law), access (art 34 of that law) and rectify (art 36 of that law) your personal data. You may thus request that your data, should it be inaccurate, incomplete, unclear, outdated, not be used or stored, be corrected, clarified, updated or deleted.
Personal information regarding our website's visitors, including their identity, is confidential.
The owners of this website hereby guarantee to respect the legal confidentiality conditions, applicable in France, and not to disclose this data to third parties.
Close
Article Outline
You can move this window by clicking on the headline