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Journal of the American Academy of Dermatology
Volume 48, n° 2S
pages 22-24 (février 2003)
Doi : 10.1067/mjd.2003.119
IgA pemphigus occurring in a 1-month-old infant

Masayuki Suzuki, MD a, Sachiko Karube, MD a, Youichi Kobori, MD a, Keitaro Usui, MD a, Satoru Murata, MD a, Hideyuki Kato, MD b, Hidemi Nakagawa, MD a
a Department of Dermatology, Jichi Medical School Tochigi, Japan 
b Saiseikai Utsunomiya Hospital. Tochigi, Japan 


An 11-month-old girl had recurrent pruritic vesiculopustular lesions involving the trunk, extremities, and scalp since the age of 1-month. Histopathologic examination revealed an intraepidermal bulla produced by acantholysis and neutrophilic spongiosis. Direct immunofluorescence showed IgA deposits in the intercellular space throughout the epidermis. Circulating anti-intercellular IgA autoantibodies were absent. Dapsone therapy was effective. (J Am Acad Dermatol 2003;48:S22-4.)

The full text of this article is available in PDF format.

 This supplement is made possible through an unrestricted educational grant from Stiefel Laboratories to the American Academy of Dermatology.
 Reprint requests: Masayuki Suzuki, Department of Dermatology, Jichi Medical School, Yakushiji Minamikawachimachi Kawachigun Tochigi 329-0498 Japan. E-mail:
 0190-9622/2003/$30.00 + 0

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