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Journal of the American Academy of Dermatology
Volume 46, n° 2
pages 187-192 (février 2002)
Doi : 10.1067/mjd.2002.119101
accepted : 2 July 2001
Lipodermatosclerosis: Review of cases evaluated at Mayo Clinic

Alison J. Bruce, MBChBa, Daniel D. Bennett, MDa, Christine M. Lohse, BSb, Thom W. Rooke, MDc, Mark D.P. Davis, MB, MRCPIa
Rochester, Minnesota 
From the Department of Dermatology,a the Section of Biostatistics,b and the Gonda Vascular Center,c Mayo Clinic and Mayo Foundation 


Background: Lipodermatosclerosis describes bound-down, sclerotic skin involving the lower extremities. Objective: Our purpose was to describe the demographic and clinical features of patients with lipodermatosclerosis. Methods: This was a retrospective study of patients presenting to Mayo Clinic between 1976 and 1998 with a diagnosis of lipodermatosclerosis. Results: Of 97 patients, 84 (87%) were women. Mean age was 62 years (range, 25-88 years). Mean body mass index was 34.3 (range, 17.8-71.5). Clinical signs were bilateral involvement in 44 patients (45%), induration localized to a discrete plaque in 49 (51%), erythema in 69 (71%), hyperpigmentation in 57 (59%), ulceration in 13 (13%), concomitant edema in 69 (71%), and varicosities in 55 (57%). Vascular studies performed on 72 patients showed abnormalities in 49: deep venous incompetence in 33 (67%), calf muscle pump abnormality in 19 (39%), abnormal pulsatility in 10 (20%), and obstruction in 1 (2%). Conclusion: Lipodermatosclerosis was associated with female sex, middle age, high body mass index, and venous abnormalities. (J Am Acad Dermatol 2002;46:187-92.)

The full text of this article is available in PDF format.

 Reprint requests: Mark D. P. Davis, Department of Dermatology, Mayo Clinic, 200 First St SW, Rochester, MN 55905.

© 2002  American Academy of Dermatology, Inc. Published by Elsevier Masson SAS@@#104157@@
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