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Journal of the American Academy of Dermatology
Volume 46, n° 2
pages 260-263 (février 2002)
Doi : 10.1067/mjd.2002.118345
In vivo examination of lentigo maligna and malignant melanoma in situ, lentigo maligna type by near-infrared reflectance confocal microscopy: Comparison of in vivo confocal images with histologic sections
 

Zeina S. Tannousa,b, Martin C. Mihma, Thomas J. Flottea, Salvador Gonzálezb
Boston, Massachusetts 
From the Dermatopathology Unit, Pathology Department,a and the Wellman Laboratories of Photomedicine, Dermatology Department,b Massachusetts General Hospital, Harvard Medical School 

Abstract

In vivo confocal microscopy can noninvasively image thin en face sections within living intact human tissue with high resolution and contrast. This evolving technique may provide clinicians with tools to help detect lentigo maligna lesion progression in vivo and may be important in defining tumor margins, thus providing a more definitive surgical eradication of lentigo maligna and malignant melanoma in situ, lentigo maligna type. We present a case of malignant melanoma in situ, lentigo maligna type, and we describe the images seen with confocal microscopy in correlation with routine histopathology. (J Am Acad Dermatol 2002;46:260-3.)

The full text of this article is available in PDF format.

 Supported in part by the US Department of Energy (grant DOE-FG0Z-91ER61228).
 Reprint requests: Salvador González, MD, PhD, Wellman Laboratories of Photomedicine, Barlett Hall 814, Department of Dermatology, Massachusetts General Hospital, 55 Blossom St, Boston, MA 02114.



© 2002  American Academy of Dermatology, Inc. Published by Elsevier Masson SAS@@#104157@@
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