A variant of acrokeratoelastoidosis in systemic scleroderma: Report of 7 cases - 01/09/11
Abstract |
We describe acrokeratoelastoidosis-like lesions on the palms of the patients with systemic scleroderma. Histology showed a focal hyperkeratosis with or without epidermal concavity, regular acanthosis, and hyalinization of collagen fibers and, in some cases, fragmentation and diminution of elastic fibers in the deep dermis. A slight degree of fibrotic change of collagen in the uninvolved neighboring skin was found in one case. The lesions were found in 7 of 26 patients with systemic scleroderma who were analyzed here, and were not found in the unrelated connective tissue disorders (n = 32) and normal controls (n = 27). The cause of the unique skin lesions may be related to the altered connective tissue metabolism similar to that of systemic scleroderma. (J Am Acad Dermatol 2002;46:767-70.)
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Reprint requests: Dr Shingo Tajima, Department of Dermatology, National Defense Medical College, 3-2 Namiki, Tokorozawa, Saitama 359-8513, Japan. E-mail: tajimas@ndmc.ac.jp. |
Vol 46 - N° 5
P. 767-770 - mai 2002 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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