Topical tacrolimus in the treatment of symptomatic oral lichen planus: A series of 13 patients - 01/09/11
Abstract |
Background: Oral lichen planus (OLP) is a relatively common, chronic inflammatory condition, which frequently presents with symptoms of pain and irritation. OLP is often difficult to manage. Therefore there is a need for more effective and safer therapies for symptomatic OLP. Objective: Our purpose was to determine the effectiveness of topical tacrolimus as therapy for symptomatic OLP. Methods: A retrospective review was performed of 13 patients with symptomatic OLP treated with topical tacrolimus between September 1999 and September 2000. Results: Eleven of the 13 patients reported definite symptomatic response to treatment and 2 had no response. Eight patients had a partial response, whereas 3 patients had a complete response with respect to lesion clearance. Seven of the responding patients had no flares with continued treatment. The other 4 patients noted flares soon after stopping the treatment. Side effects were rare and minor. Conclusions: In this retrospective case series of 13 patients, topical tacrolimus was well tolerated and appeared to be an effective therapy to control symptoms and clear lesions of OLP. (J Am Acad Dermatol 2002;46:27-34.)
Le texte complet de cet article est disponible en PDF.Plan
Funding sources: None. |
|
Conflicts of interest: None. |
|
Reprint requests: Mark D. P. Davis, MD, 200 First St SW, Rochester, MN 55905. |
Vol 46 - N° 1
P. 27-34 - janvier 2002 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
Déjà abonné à cette revue ?