Article

3 Iconography
Access to the text (HTML) Access to the text (HTML)
PDF Access to the PDF text
Advertising


Access to the full text of this article requires a subscription.
  • If you are a subscriber, please sign in 'My Account' at the top right of the screen.

  • If you want to subscribe to this journal, see our rates

  • You can purchase this item in Pay Per ViewPay per View - FAQ : 33,00 € Taxes included to order
    Pages Iconography Videos Other
    7 3 0 0


Nutrition clinique et métabolisme
Volume 20, n° 4
pages 178-184 (décembre 2006)
Doi : 10.1016/j.nupar.2006.10.179
Métabolisme des nutriments au cours de l'insuffisance respiratoire chronique
Metabolism and nutrients in chronic respiratory insufficiency
 

Claude Pichard a, , Noël José-Marie Cano b
a Unité de nutrition, hôpitaux universitaires de Genève, 24, rue Micheli-du-Crest, 1211 Genève-XIV, Suisse 
b Service de gastroentérologie et nutrition, clinique du Parc, Marseille, France 

Auteur correspondant.
Résumé

L'effet du manque d'oxygène sur le métabolisme a été largement étudié in vitro et chez l'animal, mais peu chez l'homme. Cette revue analyse la littérature concernant des situations pathologiques et physiologiques caractérisées par une exposition chronique à l'hypoxie, en particulier chez les patients souffrant d'une insuffisance respiratoire chronique et chez les sujets sains vivant en haute altitude. Ces derniers offrent un modèle de comparaison particulièrement intéressant car ils ne présentent pas les complications intercurrentes habituellement observées chez les patients porteurs d'une insuffisance respiratoire chronique. Cela permet d'apprécier l'effet exclusif de l'hypoxie sur l'organisme de l'homme sain et enrichir les connaissances encore insuffisantes chez l'homme malade.

The full text of this article is available in PDF format.
Abstract

The effect of oxygen in modulating metabolism has been largely investigated in vitro and in animal studies, but very little in humans. This paper focuses on recent literature regarding pathological and physiological situations characterized by chronic exposure to hypoxia, particularly in patients with chronic respiratory insufficiency and in healthy subjects staying at high altitude. The latest allow for very interesting comparison because they do not experience comorbidities observed in patients with chronic respiratory insufficiency and therefore provide a unique model to assess the specific effect of hypoxia on human body and metabolism.

The full text of this article is available in PDF format.

Mots clés : Hypoxie, Insuffisance respiratoire chronique, Haute altitude, HIF-1, Leptine

Keywords : Hypoxia, COPD, High altitude, HIF-1, Leptin




© 2006  Elsevier Masson SAS. All Rights Reserved.
EM-CONSULTE.COM is registrered at the CNIL, déclaration n° 1286925.
As per the Law relating to information storage and personal integrity, you have the right to oppose (art 26 of that law), access (art 34 of that law) and rectify (art 36 of that law) your personal data. You may thus request that your data, should it be inaccurate, incomplete, unclear, outdated, not be used or stored, be corrected, clarified, updated or deleted.
Personal information regarding our website's visitors, including their identity, is confidential.
The owners of this website hereby guarantee to respect the legal confidentiality conditions, applicable in France, and not to disclose this data to third parties.
Close
Article Outline