Relationship between 1,25-dihydroxycholecalciferol levels and functional outcome after hip fracture in elderly patients - 05/01/07
, Milagros Garcia-Lazaro b, Manuel Montero b, Pedro Lopez-Castro a, Francisco León a, Critobal Aguilera c
Corresponding author. Mejorana 45, 14012 Cordoba, Spain.Bienvenue sur EM-consulte, la référence des professionnels de santé.
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Abstract |
A prospective study was performed in 109 patients with osteoporotic hip fracture to verify the relationship between 1,25-dihydroxycholecalciferol levels at admission and functional recovery in elderly patients with hip fracture. 47.7% of all the patients had 1,25-dihydroxycholecalciferol levels below the reference values of our laboratory. At 1 year of the fracture only 33 patients (30.3%) had recovered the functional level they had before the fracture. In the bivariate analysis, a statistically significant relationship was found between reduced 1,25-dihydroxycholecalciferol levels and a poorer functional recovery 1 year after the fracture was sustained. A multivariate analysis showed a significant relationship between 1,25-dihydroxycholecalciferol levels and absolute dependence of the patient 1 year after the fracture (P
=0.005; OR 6.97: CI- 1.77-27.41).
Keywords : Vitamin D, Hip fracture, Muscle strength, Functional recovery
Plan
Vol 73 - N° 6
P. 729-732 - décembre 2006 Retour au numéro
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