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Journal of the American Academy of Dermatology
Volume 43, n° 1PB
pages 18-26 (juillet 2000)
Doi : 10.1067/mjd.2000.107807
Human papillomavirus infections: Epidemiology, pathogenesis, and host immune response

Stephen K. Tyring, MD, PhD
From the Departments of Dermatology, Microbiology, Immunology, and Internal Medicine, University of Texas Medical Branch, Galveston. 


Human papillomaviruses (HPVs) are ubiquitous and often cause lesions on the skin that come to the attention of the dermatologist. Skin lesions, or warts, often occur on the hands or soles of the feet and can cause embarrassment or discomfort. Genital HPV infections are transmitted by sexual contact. Infections associated with some HPV types have a high risk of progressing to carcinoma. This review discusses the molecular biology and genetics of human papillomaviruses and provides an overview of the virology, pathology, clinical manifestations, and host immune response to infection. (J Am Acad Dermatol 2000;43:S18-26.)

The full text of this article is available in PDF format.

 Stephen K. Tyring, MD, PhD, consults for 3M and is listed on the Speakers’ Bureau. Dr. Tyring’s research is supported, in part, by 3M. He does not have any financial interests in the company.

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