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Journal of the American Academy of Dermatology
Volume 42, n° 5P1
pages 727-730 (mai 2000)
Doi : 10.1067/mjd.2000.104791
accepted : 30 November 1999
Fat redistribution in HIV disease

Graham E.J. Rodwell, MD a, Toby A. Maurer, MD a, Timothy G. Berger, MD b
a Departments of Dermatology, University of California San Francisco, San Francisco General Hospital San Francisco, California 
b University of California San Francisco, Dermatology Units. San Francisco, California 


Background: Abnormal distributions of body fat have been reported in association with HIV infection, including cases of both regional loss and gain of fat. Objective: We describe the spectrum of abnormal fat distribution in HIV-positive patients. Methods: Patients were included if they demonstrated a lack of subcutaneous fat in the cheeks in the absence of generalized wasting. Patients were examined fully and photographed, and medical records were reviewed. Results: Fourteen patients were seen. Further abnormalities of body fat distribution were noted in all patients. We found a consistent pattern of fat loss in the cheeks, temples, and extremities as well as fat gain over the neck, upper back, mastoid processes, chest, and visceral abdomen. Conclusion: A consistent syndrome of body fat redistribution is seen in HIV-positive patients. A characteristic pattern of fat loss in the cheeks may serve as a specific marker of HIV-related fat redistribution. (J Am Acad Dermatol 2000;42:727-30.)

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 Reprint requests: Toby A. Maurer, MD, Department of Dermatology, University of California San Francisco, San Francisco General Hospital, Room 224, Ward 92, Bldg 90, 1001 Potrero Ave, San Francisco, CA 94110. E-mail:

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