Mast cells in an angiosarcoma complicating Xeroderma pigmentosum in a 13-year-old girl - 05/09/11
Abstract |
A cutaneous angiosarcoma, a rare tumor that occurs almost exclusively in sunexposed skin of individuals older than 50 years, developed in an adolescent with Xeroderma pigmentosum (XP). As this is the second report of a child with angiosarcoma and XP, ultraviolet-induced DNA damage may be involved in the pathogenesis of this tumor. Strongly increased numbers of mast cells were found, particularly in the peripheral tumor area, which may reflect with the requirement of mast cells for the growth of vascular structures or a role for mast cells in the antitumor immune response. (J Am Acad Dermatol 2000;43:900-2.)
Le texte complet de cet article est disponible en PDF. | Supported by project B6 of the SFB 469 of the Deutsche Forschungsgemeinschaft. |
Vol 43 - N° 5PB
P. 900-902 - novembre 2000 Retour au numéro
Article précédent
- Stevens-Johnson syndrome associated with concomitant use of lamotrigine and valproic acid
- Başak Yalçin, Ayşen Karaduman
- A case of extragenital lichen sclerosus following Blaschko's lines
- Sung Woo Choi, Jeong Eun Yang, Hyun Jeong Park, Chung Won Kim
Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
Déjà abonné à cette revue ?