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Journal of the American Academy of Dermatology
Volume 42, n° 3
pages 490-492 (mars 2000)
Doi : 10.1016/S0190-9622(00)90224-X
Potassium iodide and the Wolff-Chaikoff effect: Relevance for the dermatologist

Warren R. Heymann, MD
Division of Dermatology, UMDNJ–Robert Wood Johnson School of Medicine. Marlton, New Jersey 


The inhibition of organic binding of iodide in the thyroid gland by excess iodide, resulting in the cessation of thyroid hormone synthesis, is known as the Wolff-Chaikoff effect. This review explores the nature of the Wolff-Chaikoff effect, both in terms of its potential mechanisms and its relevance to dermatologists who use potassium iodide as a therapeutic agent. (J Am Acad Dermatol 2000;42:490-2.)

The full text of this article is available in PDF format.

 Reprint requests: Warren R. Heymann, MD, Head, Division of Dermatology, UMDNJ–Robert Wood Johnson School at Camden, 100 Brick Road, Ste 306, Marlton, NJ 08053.

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