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Journal of the American Academy of Dermatology
Volume 42, n° 3
pages 514-515 (mars 2000)
Doi : 10.1016/S0190-9622(00)90231-7
Pemphigus foliaceus successfully treated with mycophenolate mofetil as a steroid-sparing agent

Kenneth H. Katz, MD, James G. Marks, MD, Klaus F. Helm, MD
Department of Medicine, Section of Dermatology, Penn State University, Milton S. Hershey Medical Center. Hershey, Pennsylvania 


Pemphigus foliaceus is an autoimmune blistering disease of unknown origin with antibodies produced against desmoglein 1, an adhesive protein found in the desmosomal cell junction in the suprabasal layers of the epidermis. The disease is primarily treated with corticosteroids and corticosteroid-sparing immunosuppressive agents. We report a case of pemphigus foliaceus successfully treated with mycophenolate mofetil. It remains to be seen whether this agent has a significant effect on the course of the disease and remission induction. (J Am Acad Dermatol 2000;42:514-5.)

The full text of this article is available in PDF format.

 Reprint requests: Kenneth H. Katz, MD, Penn State, Department of Medicine, Section of Dermatology, The Milton S. Hershey Medical Center, Hershey, PA 17033.

© 2000  American Academy of Dermatology, Inc. Published by Elsevier Masson SAS@@#104157@@
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