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Journal of the American Academy of Dermatology
Volume 42, n° 5P2
pages 859-861 (mai 2000)
Doi : 10.1016/S0190-9622(00)90253-6
Development of pemphigus vulgaris in a patient with pemphigus foliaceus: Antidesmoglein antibody profile shift confirmed by enzyme-linked immunosorbent assay

Ken Ishii, MDa,b, Masayuki Amagai, MD, PhDa, Yoshiyuki Ohata, MDa, Hiroshi Shimizu, MDa, Takashi Hashimoto, MDc, Kazuhiko Ohya, d, Takeji Nishikawa, MDa
Tokyo, Fukuoka, and Nagoya, Japan 
From Department of Dermatology, Keio University School of Medicine,a Saiseikai Central Hospital,b Tokyo; Kurume University School of Medicine, Fukuokac; and Medical and Biological Laboratories, Nagoya.d 


We describe a patient with pemphigus foliaceus (PF) in whom pemphigus vulgaris (PV) subsequently developed. The clinical change was accompanied by a shift of autoantibody profile confirmed by enzyme-linked immunosorbent assay. Antidesmoglein (Dsg) 1 antibodies alone were detected in the PF stage, whereas both anti-Dsg3 and anti-Dsg1 antibodies were detected in the PV stage. (J Am Acad Dermatol 2000;42:859-61.)

The full text of this article is available in PDF format.

 This supplement is made possible through an educational grant from Ortho Dermatological to the American Academy of Dermatology.
 Reprint requests: Ken Ishii, MD, Department of Dermatology, Keio University School of Medicine, 35 Shinanomachi Shinjuku-ku, Tokyo, 160-8582, Japan. E-mail: .

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