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Journal of the American Academy of Dermatology
Volume 42, n° 5P2
pages 867-868 (mai 2000)
Doi : 10.1016/S0190-9622(00)90256-1
A painful cutaneous nodule as the presentation of metastatic transitional cell carcinoma of the renal pelvis

Matthew J. Zirwas, BSa, Susan Hunt, MDb, Theodore F. Logan, MDc, John L. Abernethy, MDd, Mark P. Seraly, MDd
Pittsburgh, Pennsylvania 
From the University of Pittsburgh School of Medicine,a the Departments of Internal Medicineb and Dermatology,d and the Pittsburgh Cancer Institute,c University of Pittsburgh Medical Center 


We report a 43-year-old man with HIV who presented with a painful, vascular-appearing nodule as the initial manifestation of metastasis of a prior transitional cell carcinoma of the renal pelvis. The transitional cell carcinoma had been treated by nephroureterectomy 4 years before the appearance of the nodule. Histopathologic comparison of the nodule with the prior transitional cell carcinoma and immunoperoxidase staining with monoclonal antibodies confirmed that the nodule was a metastasis of the original transitional cell carcinoma. In general, metastasis of transitional cell carcinoma to the skin is quite uncommon. This case is the first reported episode of transitional cell carcinoma of the renal pelvis metastasizing to the skin in the form of a vascular-appearing nodule. The significance of this unusual metastasis occurring in a person with HIV is unknown. (J Am Acad Dermatol 2000;42:867-8.)

The full text of this article is available in PDF format.

 This supplement is made possible through an educational grant from Ortho Dermatological to the American Academy of Dermatology.
 Reprint requests: Mark P. Seraly, MD, Falk Ambulatory Center, Department of Dermatology, 3601 Fifth Ave, Pittsburgh, PA 15213. E-mail: seralymp@MSX.UPMC.EDU.

© 2000  American Academy of Dermatology, Inc. Published by Elsevier Masson SAS@@#104157@@
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