Cowpox virus infection in an 11-year-old girl

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Journal of the American Academy of Dermatology
Volume 42, n° 5P2
pages 892-894 (mai 2000)

Doi : 10.1016/S0190-9622(00)90265-2

Cowpox virus infection in an 11-year-old girl

Ralf Wienecke, MD ^a, Hans Wolff, MD ^a, Martin Schaller, MD ^a, Hermann Meyer, DVM ^b, Gerd Plewig, MD ^a
^a Department of Dermatology and Allergology, Klinikum Innenstadt, Ludwig-Maximilians-University Munich Munich, Germany
^b Institute of Microbiology, Federal Armed Forces Medical Academy Munich. Munich, Germany


	Abstract

We describe an 11-year-old girl with a cowpox virus infection, who presented with a 14-day-old crusted, ulcerated nodule on the chin/neck and a 6-day-old eroded blister on the left leg. The girl lived in a rural environment, had close contact to several cats from the neighborhood, and had an atopic predisposition. The presence of orthopox virus in the lesion on the left leg was demonstrated by electron microscopy (negative staining, transmission electron microscopy) and virus isolation. Classification as a cowpox virus was determined by polymerase chain reaction (PCR), followed by restriction enzyme digestion of the PCR product. (J Am Acad Dermatol 2000;42:892-4.)

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	This supplement is made possible through an educational grant from Ortho Dermatological to the American Academy of Dermatology.
	Reprint requests: Ralf Wienecke, MD, Department of Dermatology and Allergology, Ludwig-Maximilians-University Munich, Frauenlobstr. 9-11, 80337 Munich, Germany.

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