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Journal of the American Academy of Dermatology
Volume 42, n° 5P2
pages 927-928 (mai 2000)
Doi : 10.1016/S0190-9622(00)90274-3
Scleromyxedema with dermato-neuro syndrome

Joselyn Gonzalez, MDa,b, Mark Palangio, MSc, Joseph Schwartz, MDa, Albert S. Klainer, MDb,c, Emil Bisaccia, MDa,d
Morristown, New Jersey, and New York, New York 
From the Section of Photopheresisa and Department of Internal Medicine,b Morristown Memorial Hospital, and the Departments of Medicinec and Dermatology,d Columbia University College of Physicians and Surgeons, New York 


Scleromyxedema is a rare connective tissue disease of unknown cause characterized by a generalized papular eruption, dermal fibroblast proliferation, and monoclonal paraproteinemia. A paroxysmal triad consisting of high fever, seizures, and coma with a flu-like prodrome can rarely occur in patients with scleromyxedema and is termed “dermato-neuro syndrome.” We describe a 41-year-old patient with scleromyxedema in whom the dermato-neuro syndrome developed. (J Am Acad Dermatol 2000;42:927-8.)

The full text of this article is available in PDF format.

 This supplement is made possible through an educational grant from Ortho Dermatological to the American Academy of Dermatology.
 Reprint requests: Emil Bisaccia, MD, Morristown Memorial Hospital, 100 Madison Ave, Morristown, NJ 07962-1956.

© 2000  American Academy of Dermatology, Inc. Published by Elsevier Masson SAS@@#104157@@
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