Low-dose oral methotrexate treatment for recalcitrant palmoplantar pompholyx - 07/09/11
Abstract |
We describe 5 patients with severe pompholyx who did not respond to conventional therapy or who had debilitating side effects from corticosteroids. Low-dose methotrexate was added to their treatment regimens and led to significant improvement or clearing with a favorable side-effect profile. In all 5 patients the need for oral corticosteroid therapy was substantially decreased or eliminated, thus decreasing potential corticosteroid-induced morbidity. In this uncontrolled series of patients with recalcitrant palmoplantar pompholyx, methotrexate was an effective treatment and acted as a steroid-sparing agent. (J Am Acad Dermatol 1999;40:612-4.)
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Reprint requests: Conleth A. Egan, MB, MRCPI, Department of Dermatology, University of Utah School of Medicine, Salt Lake City, UT 84132. |
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0190-9622/99/$8.00 + 0 16/1/96380 |
Vol 40 - N° 4
P. 612-614 - avril 1999 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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