Ovarian cancer presenting as leukocytoclastic vasculitis - 07/09/11
Abstract |
We describe a 53-year-old woman with a 4-month history of palpable purpuric papules on the upper and lower extremities. Biopsy of the skin lesions revealed leukocytoclastic vasculitis. Although she denied any systemic symptoms, urinalysis demonstrated hematuria and proteinuria. Although the patient’s skin lesions responded to prednisone, her urinalysis did not improve. A 10-cm complex mass involving the left ovary and adnexa was incidentally discovered on renal ultrasound. Serum CA-125, an ovarian cancer marker, was elevated. Laparotomy revealed ovarian carcinoma confined to the left ovary. After the cancer was resected, the patient’s urinalysis slowly improved. Leukocytoclastic vasculitis (LCV) is infrequently associated with underlying malignancy and only rarely with solid tumors. We postulate that the patient’s vasculitis represented a paraneoplastic phenomenon that allowed a diagnosis of asymptomatic ovarian carcinoma. To our knowledge, this is the first report of LCV occurring as the presenting sign of ovarian cancer. (J Am Acad Dermatol 1999;40:287-9.)
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This supplement is made possible through an education grant from Ortho Dermatological to the American Academy of Dermatology. |
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The opinions or assertions contained herein are the private views of the authors and are not to be construed as official or as reflecting the views of the Departments of the Navy, Army or the Department of Defense. |
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16/4/95182 |
Vol 40 - N° 2S
P. 287-289 - février 1999 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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