Adult-onset angiofibroma and multiple endocrine neoplasia type I - 07/09/11
Abstract |
Multiple endocrine neoplasia type 1 (MEN 1) predisposes affected persons to neoplasms of the parathyroid glands, the endocrine pancreas, the anterior pituitary, and the duodenum. We report the first case of adult-onset multiple angiofibromas of the central face associated with MEN 1. Seven siblings also developed adult-onset angiofibromas, none with evidence of tuberous sclerosis. Basic fibroblast growth factor (BFGF) is elevated in many patients with MEN 1 and may play a pathogenetic role. (J Am Acad Dermatol 1999;41: 890-2.)
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From the Departments of Dermatology and Clinical Research, Naval Medical Center, San Diego. |
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The Chief, Bureau of Medicine and Surgery, Navy Department, Washington, DC, Clinical Investigation Program sponsored this report no. 84-16-1968-719, as required by NSHSBETHINST 6000.41A. |
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Reprint requests: Major T. A. Hoang-Xuan, MC, USA, c/o Clinical Investigation Department, Naval Medical Center San Diego, 34800 Bob Wilson Dr, Suite 5, San Diego, CA 92134-1005. E-Mail: hoangxuan@pol.net |
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16/4/101592 |
Vol 41 - N° 5S
P. 890-892 - novembre 1999 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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