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Doi : 10.1016/S1634-7072(07)48677-9
Paralisi sopranucleare progressiva (malattia di Steele-Richardson-Olszewski )

F. Dubas a,  : Professeur des Universités, praticien hospitalier, J. Cassereau a : Interne, P. Lejeune b : Praticien hospitalier
a Département de neurologie, Hôpital Larrey, centre hospitalier universitaire, 49000 Angers, France 
b Service de neurologie, centre hospitalier, Les Oudaries, boulevard Stéphane-Moreau, 85925 La-Roche-Sur-Yon, France 

Indirizzo per la corrispondenza.

La paralisi sopranucleare progressiva (PSP o malattia di Steele-Richardson-Olszewski) è la seconda causa in ordine di frequenza di parkinsonismo, dopo la morbo di Parkinson. L'età di esordio media è di 60 anni. È caratterizzata da acinesia assiale, paralisi della verticalità dello sguardo, distonia cervicale in estensione, sindrome pseudobulbare e sindrome sotto-corticofrontale. La conferma della diagnosi spetta allo studio neuropatologico, con una perdita neuronale e degenerazioni neurofibrillari del tronco cerebrale.

The full text of this article is available in PDF format.

Parole chiave : Sindrome parkinsoniana, Oftalmoplegia, Sindrome sotto-corticofrontale, tauopatia

© 2007  Elsevier Masson SAS. All Rights Reserved.

@@#116875@@ : F. Dubas, J. Cassereau, P. Lejeune. Paralisi sopranucleare progressiva (malattia di Steele-Richardson-Olszewski ). EMC - Neurologia 2007:1-12 [Article 17-062-B-10].

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