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Archives de pédiatrie
Volume 14, n° 3
pages 306-309 (mars 2007)
Doi : 10.1016/j.arcped.2007.01.004
La coqueluche en pratique en 2007
Pertussis in practice in 2007
 

E. Grimprel
Consultation, urgences pédiatriques, pathologie infectieuse et tropicale, hôpital d'enfants Armand-Trousseau, 26, avenue du Docteur-Arnold-Netter, 75571 Paris cedex 12, France 

Résumé

L'épidémiologie de la coqueluche s'est transformée sous l'effet de la vaccination. La coqueluche est désormais fréquente chez l'adolescent et l'adulte mais méconnue, ce qui contribue à la pérennisation de la circulation de Bordetella pertussis en France et à la contamination de jeunes nourrissons qui font les formes les plus sévères. Le contrôle de la transmission de la coqueluche en France nécessite le renforcement de la vaccination par la pratique de rappels vaccinaux tardifs chez l'adolescent et l'adulte mais également la formation des médecins à la reconnaissance précoce des cas de coqueluche, en particulier chez l'adolescent et l'adulte, devant une toux persistante ou chronique et la mise en place des mesures prophylactiques (antibiothérapie et rappel vaccinal) autour des cas confirmés. Le traitement curatif est peu efficace sur les symptômes mais il réduit la contagiosité. Il repose sur les macrolides.

The full text of this article is available in PDF format.
Abstract

Universal vaccination of infants against pertussis has transformed the epidemiology of the disease. Pertussis has however become frequent, although not often diagnosed, in adolescents and adults and thus contributes to permanent transmission of Bordetella pertussis in France and contamination of young infants at risk of severe disease. Control of transmission of pertussis in France necessitates reinforcement of vaccination with late boosters in adolescents and adults and, in addition, education of physicians to recognize and treat early cases ofpertussis, especially in adolescents and adults with a persistant or chronic cough, and to take appropriate prophylactic measures (antibiotics and recall vaccination) of those in contact with confirmed cases. Effective treatment does little to reduce symptoms but it does reduce transmission. Macrolides are the recommended treatment for pertussis.

The full text of this article is available in PDF format.

Mots clés : Coqueluche, Bordetella pertussis , Vaccination, Macrolides

Keywords : Pertussis, Whooping cough, Bordetella pertussis , Vaccination, Macrolides



 Article paru dans la Revue française d'allergologie et d'immunologie clinique 2006; 46: 548-51 et réactualisé en 2007.
 Congrès francophone pédiatrique de pneumologie et d'allergologie ; 17 novembre 2006.



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