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Journal of the American Academy of Dermatology
Volume 38, n° 5S
pages 860-861 (mai 1998)
Doi : 10.1016/S0190-9622(98)70476-1
Use of topical cyclosporin in oral pemphigus

C. Gooptu, MRCPa, R.C.D. Staughton, FRCPb
Oxford and London, United Kingdom 
From The Oxford Radcliffe Hospital, Oxford,a and Chelsea and Westminster Hospital London. b 


The use of systemic cyclosporin in the treatment of pemphigus is well recognized. Oral lesions in pemphigus vulgaris are common but can be very difficult to treat. Short use of topical cyclosporin has been reported in a few cases of oral pemphigus. We report the successful use of topical cyclosporin for several years in a patient with debilitating oral pemphigus in whom systemic immunosuppressive agents and topical steroids had been ineffective and in whom cyclosporin was used not only to induce but also to maintain remission. (J Am Acad Dermatol 1998;38:860-1.)

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 This article is made possible through an educational grant from Ortho Dermatological.
 Reprint requests to: Chandra Gooptu, MRCP, Dermatology Department, The Oxford Radcliffe Hospital, Oxford, OX3 7LJ, United Kingdom.
 0190-96222/98/$5.00 + 0   16/4/86461

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