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Journal of the American Academy of Dermatology
Volume 38, n° 5S
pages 862-865 (mai 1998)
Doi : 10.1016/S0190-9622(98)70477-3
Cutaneous malignant melanoma and oculodermal melanocytosis (nevus of Ota): Report of a case and review of the literature

Bhupendra C.K. Patel, MD, FRCS, FRCOphtha, Conleth A. Egan, MB, MRCPIb, Richard W. Lucius, MDa, John W. Gerwels, MDb, Nick Mamalis, MDa, Richard L. Anderson, MDa
Salt Lake City, Utah 
From the Departments of Ophthalmologya and Dermatology,b University of Utah Health Sciences Center, Salt Lake City 


A 29-year-old white man, with oculodermal melanocytosis, had a rapidly enlarging, erythematous, painful nodule over his left brow, within the nevus. The lesion was excised and diagnosed as a malignant melanoma. Systemic evaluation showed no evidence of distant disease. This is the tenth case reported of a cutaneous melanoma developing in a nevus of Ota. Melanoma arising in the choroid, brain, orbit, iris, ciliary body, or optic nerve in association with a nevus of Ota is well documented. Careful observation is necessary in patients with a nevus of Ota, particularly in white patients, in whom malignant degeneration seems to occur with a disproportionate frequency. (J Am Acad Dermatol 1998;38:862-5.)

The full text of this article is available in PDF format.

 This article is made possible through an educational grant from Ortho Dermatological.
 Reprint requests to: Conleth A. Egan, Department of Dermatology, University of Utah Health Sciences Center, 50 North Medical Dr., Salt Lake City, UT 84132.
 0190-9622/98/$5.00 + 0   16/4/85742

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