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Journal of the American Academy of Dermatology
Volume 38, n° 1
pages 1-20 (janvier 1998)
Doi : 10.1016/S0190-9622(98)70532-8
Nonneoplastic disorders of the eccrine glands
 

Frederick G. Wenzel, MD, Thomas D. Horn, MD*
Baltimore, Maryland 

Abstract

Eccrine glands are uniquely susceptible to a variety of pathologic processes. Alteration in the rate of sweat secretion manifests as hypohidrosis and hyperhidrosis. Obstruction of the eccrine duct leads to miliaria. The excretion of drugs into eccrine sweat may be a contributory factor in neutrophilic eccrine hidradenitis (NEH), syringosquamous metaplasia (SSM), coma bulla, and erythema multiforme (EM). Alterations in the electrolyte composition of eccrine sweat can be observed in several systemic diseases, most notably cystic fibrosis. This article summarizes current knowledge of eccrine gland pathophysiology. (J Am Acad Dermatol 1998;38:1-17.)

The full text of this article is available in PDF format.

 From the Department of Dermatology, The Johns Hopkins School of Medicine.
 Reprint requests: Thomas D. Horn, MD, Department of Dermatology, Division of Dermatopathology, The Johns Hopkins University School of Medicine, Blalock 907, 600 N. Wolfe St., Baltimore, MD 21287.
 *Dr. Horn is now at the Department of Dermatology, University of Arkansas for Medical Sciences, Slot 576, 4301 W. Markham St., Little Rock, AR 72205-7199.
 16/2/86471



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