Access to the text (HTML) Access to the text (HTML)
PDF Access to the PDF text

Access to the full text of this article requires a subscription.
  • If you are a subscriber, please sign in 'My Account' at the top right of the screen.

  • If you want to subscribe to this journal, see our rates

Journal of the American Academy of Dermatology
Volume 38, n° 1
pages 21-26 (janvier 1998)
Doi : 10.1016/S0190-9622(98)70533-X
accepted : 4 August 1997
Low-dose UVA1 phototherapy for treatment of localized scleroderma

Martina Kerscher, MDa, Matthias Volkenandt, MDb, Claus Gruss, MDa, Tilmann Reuther, MDa, Gregor von Kobyletzki, MDa, Marcus Freitag, MDa, Thomas Dirschka, MDa, Peter Altmeyer, MDa
Bochum, Munich, and Düsseldorf, Germany 


Background: For treatment of localized scleroderma numerous treatments, including ones with potentially hazardous side effects, are currently used with only limited success. Objective: We attempted to determine the efficacy of low-dose UVA1 irradiation in patients with severe localized scleroderma. Methods: Patients were irradiated with 20 J/cm 2 UVA1 for 12 weeks (total number of treatments: 30; cumulative UVA1 dose: 600 J/cm2). Results: Low-dose UVA1 irradiation induced significant clinical improvement (clearance of>80% of lesions) in 18 of 20 patients. Clearance was documented by clinical score as well as by 20 MHz ultrasound and histopathologic analysis. Conclusion: Low-dose UVA1 phototherapy can be highly effective for sclerotic plaques, even in patients with advanced localized scleroderma and with lesions rapidly evolving despite conventional therapy. (J Am Acad Dermatol 1998;38:21-6.)

The full text of this article is available in PDF format.

 From the Departments of Dermatology, Ruhr-University Bochum, a Ludwig-Maximilians University Munich,b and Heinrich-Heine University Düsseldorf.c
 Reprint requests: Martina Kerscher, MD, Department of Dermatology, Ruhr-University Bochum, Gudrunstrasse 56, D-44791 Bochum, Germany.

© 1998  Mosby, Inc. All Rights Reserved.
EM-CONSULTE.COM is registrered at the CNIL, déclaration n° 1286925.
As per the Law relating to information storage and personal integrity, you have the right to oppose (art 26 of that law), access (art 34 of that law) and rectify (art 36 of that law) your personal data. You may thus request that your data, should it be inaccurate, incomplete, unclear, outdated, not be used or stored, be corrected, clarified, updated or deleted.
Personal information regarding our website's visitors, including their identity, is confidential.
The owners of this website hereby guarantee to respect the legal confidentiality conditions, applicable in France, and not to disclose this data to third parties.
Article Outline