The utility of fine needle aspiration in the diagnosis of melanoma metastatic to lymph nodes - 11/09/11

Doi : 10.1016/S0190-9622(97)80216-2

Geoffrey C. Basler, MD ^a, Darrell J. Fader, MD ^a, Alan Yahanda, MD ^b, Vernon K. Sondak, MD ^b, Timothy M. Johnson, MD ^a,^c,^d,^⁎
^a Department of Dermatology, University of Michigan Medical Center, and University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan, USA
^b Department of Surgery, University of Michigan Medical Center, and University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan, USA
^c Division of Plastic Surgery, University of Michigan Medical Center, and University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan, USA
^d Otolaryngology, University of Michigan Medical Center, and University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan, USA

¹Reprint requests: Timothy M. Johnson, MD, University of Michigan, Department of Dermatology, 1910 Taubman Center, Box 0314, Ann Arbor, MI 48109-0314.

Abstract

Background:

Prompt and accurate diagnosis of melanoma metastatic to the lymph nodes is important with respect to prognosis and treatment.

Objective:

The purpose of this study was to determine the utility and diagnostic reliability of fine needle aspiration (FNA) of enlarged nodules in lymph node basins in patients with melanoma.

Methods:

We retrospectively reviewed the charts of 46 patients with melanoma who under-went a total of 56 FNAs of palpable nodules in lymph node basins.

Results:

Of the 56 FNAs, 24 showed melanoma, 26 did not demonstrate melanoma, five were inadequate, and one gave inconclusive but suspect results. Findings were confirmed by open biopsy (n = 35) or clinical follow-up (n = 21). Fifty of 56 FNAs (89%) yielded a definitive diagnosis (sensitivity/specificity = 100% in these 50).

Conclusion:

FNA biopsy of enlarged palpable nodules in nodal basins in patients with melanoma is accurate, rapid, and cost-efficient. An algorithm for management of patients with melanoma who have palpable nodes is provided.

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Vol 36 - N° 3

P. 403-408 - mars 1997 Retour au numéro

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The utility of fine needle aspiration in the diagnosis of melanoma metastatic to lymph nodes - 11/09/11

Abstract

Background:

Objective:

Methods:

Results:

Conclusion:

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