Recurrence rates of excised keloids treated with postoperative triamcinolone acetonide injections or interferon alfa-2b injections - 11/09/11
Abstract |
Background: Keloids that are surgically removed commonly recur within the excision sites. Objective: Our purpose was to determine whether postsurgical adjunctive therapy reduces such recurrences. Methods: We determined the rate of recurrence after excision alone ( n = 43) and postoperative injection with triamcinolone acetonide (TAC; n = 65) or interferon alfa-2b (IFN-⍺2b; n = 16). Results: Of lesions excised without postoperative injections, 51.1% (22 of 43) recurred; 58.4% of TAC-treated lesions (38 of 65) recurred and 18.7% of IFN-⍺2b–treated lesions (3 of 16) recurred ( p = 0.025). Conclusion: Postoperative TAC injections do not reduce the number of keloid recurrences. However, injection of keloid excision sites with IFN-⍺2b offers a therapeutic advantage over keloid excision. (J Am Acad Dermatol 1997;37:755-7.)
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 | Reprint requests: Brian Berman, MD, PhD, University of Miami School of Medicine, Department of Dermatology and Cutaneous Surgery, 1600 NW 10th Ave., Miami, FL 33136. |
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Vol 37 - N° 5
P. 755-757 - novembre 1997 Retour au numéro
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